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|Selected mini-abstracts from the 2nd Congress World Association for Laser Therapy, September 2-5, 1998|
|Histometrical Evaluation of the Healing of the Dental Alveolus in Rats||Parizotto tenectomized the achilles tendons|
|Lymphadenitis Oasevich I A, Shargorodskii A G||Onac compared the effect of HeNe laser and monochromatic light at 618 nm.|
|Wound healing Waynant R, US Food & Drug Administration: results from a preliminary wound healing trial.||Asagai reports on the use of GaAlAs (100 mW)|
|Nerve effects a) Ohno T. Pain suppressive effect of low power laser irradiation.||Katsuyama studied the effect of 830 nm laser|
|The effect of laser irradiation on the activation of inflammatory cells and the vital pulpotomy.||Phantom pain after amputations In a study by Amaral 15 mice received|
acupuncture special: recent reports:
||In an animal study by Kobayashi the effect of GaAlAs laser|
|Reports from Laser Medicine and Surgery, Florida. April 16-18||Schindl treated a chronic radiation ulcer with HeNe laser, 30 J/cm2|
|Low-energy laser irradiation affects satellite cell proliferation and differentiation in vitro||55 patients with long lasting chronic venous ulcers,|
|Links to LLLT-Science||6 years study, Soriano treated 231 patients|
|LLLT is as well documented as NSAIDs and steroid injections for shoulder tendinitis/bursitis and epicondylaglia.||Acute nonspecific epididymitis, by Gomberg|
Rosane F. Z. Lizarelli*; Tereza L. Lamano-Carvalho**; Luis G. Brentegani** *Physics Institute of São Carlos, University of São Paulo, São Carlos, SP, Brazil. 13560-970 **College of Dentistry of Ribeirao Preto, University of São Paulo, Ribeirao Preto, SP, Brazil. 14.040-000 LIZARELLI, R. F. Z.; LAMANO-CARVALHO, T. L.; BRENTEGANI, L. G.
Histometrical evaluation of the healing of the dental alveolus
in rats after irradiation with a low-powered GaAlAs laser. in
Lasers in Dentistry V, John D. B. Featherstone, Peter Rechmann,
D.D.S., Daniel Fried, Editors, Proceedingsof SPIE Vol. 3593, p.
49-56, 1999. ABSTRACT The aim of the present work was to evaluate
histometrically the effect of the irradiation with semiconductor
diode GaAlAs 790 nm low-powered laser in the chronology of alveolar
repair of rats.
Wound healing Waynant R, US Food
& Drug Administration: results from a preliminary wound healing
A pilot study used six Sprague-Dawley rats - three
controls with no treatment and three that were irradiated for
250 seconds with 630 nm. All rats were wounded on both hips -
an 8mm circular full thickness hole. The irradiated rats received
the 630nm 5 J/cm2 dose on only the left hip. The animals were
irradiated one hour after the wounds were given and then one dose
per day for four days. The results are: ten days after wounding
the closure on the control rats averaged 26%, but irradiated rats
averaged a closure of 65% on both left (irradiated) and right
hips - a systemic effect on the right, as it received no irradiation.
The clinical course of acute nonspecific lymphadenitis of the face and neck was studied in 241 patients aged 1-14 years, in order to improve the diagnosis and therapy of this condition. General clinical examinations were supplemented by laser biophotometry and assessment of the activities of some local defense factors (lysozyme, beta-lysine, secretory and serum IgA). Multiple-modality treatment for the first time included magnetic laser therapy (MLT), and its efficacy was assessed. Results of biophotometry helped define the objective criteria for the diagnosis and evaluation of the treatment efficacy in children with acute lymphadenitis of the face and neck. MLT proved to be a highly effective treatment modality, decreasing the inflammation and correcting oral factors. Use of MLT accelerated all phases of the inflammatory process, promoted its regression at the serous stage, and decreased the incidence of suppurative forms of acute lymphadenitis by 40%.
Under anesthesia, the right sciatic nerve of 41 rats was exposed. 13 rats received laser irradiation and electrical stimulation, 16 rats only electrical stimulation and 12 served as control. Immediately after the electrical stimulation, with or withour laser irradiation, DRG of the 4th to 6th lumbar spinal roots were excised. Immunohistochemical substance P staining and substance P-like immunoreactivity (SP-LI) quantification were done in the excised DRG. There was a statistically significant difference of SP-LI between the control group and the stimulated group. There was no statistically significant difference between the laser irradiation only group and control. These results suggest that laser irradiation suppresses the exitation of the unmyelinated C-fibers in the afferent sensory pathway.
b) Tsuchiya K et al. Diode laser irradiation selectively diminishes slow component of axonal volleys to dorsal roots from the saphenous nerve. Neuroscience Letters. 1993; 161: 65-68.
GaAlAs laser irradiation inhibited the action potentials
in the dorsal roots eleicited from the spahenous nerve of the
rat. After 830 nm irradiation to the nerve, the amplitude of slower
conduction parts of action potentials( <12 m/s) were suppressed.
The suppression was dose dependent. After 3 minutes of irradiation
the slowest conduction velocity group (<1.3 m/s) were totally
diminished and the 1.3-12 m/s group were reduced to 12-67%. In
contrast, faster component(>12 m/s) was unaffected by the irradiation.
It is suggested that laser irradiation may selectively target
fibers conducting at slow velocities which include afferent axons
The effects of GaAs on the activation of machrophages
and fibroblasts were examined be determinating the rate of glucose
utilization into the cell and the activity of lactate dehydrogenase
in culture supernatant. The irradiated macrophages that had been
prepared from the perioneal exudate cells, did not show any enhancement
of activity, whereas the fibroblast cell line was activated by
Laser acupuncture special:
Schlager A et al. Laser stimulation of acupuncture point P6 reduces postoperative vomiting in children undergoing strabismus surgery. Br J Anesth. 1998; 81 (4): 529-532.
Abstracts of ICMART '97 International Medical Acupuncture
Symposium, Nicosia, Cyprus, March 26-29 1997:
2) Laserpuncture in patients with rheumatoids arthritis.
3) Application of laser acupuncture in the treatment
of periarthritis humeroscapularis.
The effect of low intensity semi conductor laser
was used as treatment methods for periarthritis humeroscapularis.
The CC laser (Computer Controlled laser) was applied.
4) Laser therapy and immunostimulators in patients
with acute orofacial infections.
The acute orofacial infections often are therapeutical
problem. The complex treatment of such patients include antimicrobial
agents, surgical intervention, immunostimulation with Oxyrich
and laser therapy.
5) Low level laser in the treatment of ulcus cruris
Z. Trojacanec, S. Nikolic, Z. Handziski Institute of ME Physiology, Faculty of Medicine, Skopje, FYROM
Ulcus cruris is a complication following deep vein
incompetence and the terms "postphlebetic leg" or "stasis syndrome"
are applied. The ulceration is usually small, superficial, and
very painful because of exposure of nerve endings. Varicose veins
may be seen or palpated close to or continuous with the ulcer.
These ulcerations may start after minor trauma to an area of pigmentation,
induration, eczema, or edema, and are usually chronic by the time
they are seen.
The process of skeletal muscle regeneration following injury
is characterized by necrosis of muscle tiusse, local inflammation
and proliferation of satellite cells that further fuse to form
multinucleated myotubes. Satellite cells, considered as the
precursor cells in the process of muscle regeneration following
injury, are normally quiescent, and are activated by factors
released from the injured muscle fibers. In a in vitro study
by Ben-Dov et al HeNe laser irradiation was shown to significantly
promote the proliferation of satellite cells in a dose-dependent
manner. Too high doses caused an inhibition. It is suggested
that HeNe irradiation activates early cell-cycle genes in satellite
cells. leading to increased proliferation and to a delay in
|LLLT is as well documented as
NSAIDs and steroid injections for shoulder tendinitis/bursitis and
The Norwegian physiotherapist Jan M Bjordal published his thesis “Low level laser therapy in shoulder tendinitis/bursitis, epicondylalgia and ankle sprain” in 1997, at the Division of Physiotherapy Science, University of Bergen. It has also been published in Physical Therapy Reviews. 1998; 3: 121-132.
Here is the Conclusion of the thesis: “A systematic review has been performed on the effect of LLLT for three diagnoses. LLLT was evaluated on similar criteria for methodological assessments of trials as previously established for medical interventions. No evidence was found to indicate that randomized controlled trials on LLLT for tendinitis/bursitis of the shoulder, lateral epicondylalgia and ankle sprains were methodologically inferior to RCTs on medical interventions. The clinical effects of LLLT were found to be supported by scientific evidence regarding short (0-4 weeks) and medium term (<3 months) efficacy for subacute or chronic lateral epicondylitis, and short term efficacy (>3 months) for subacute or chronic lateral epicondylitis, and short term efficacy (> 3 months) for subacute or chronic shoulder tendinitis/bursitis. The evidence of effect from LLLT for acute ankle sprain in inconclusive, although there seems to be a slight tendency in favour of LLLT. Adverse effects of LLLT are rarely seen and only in minor forms (nausea, headache) compared to medication, where more serious gastrointestinal discomfort or ulcers are not uncommon. It has also been shown that trials in favour of active treatment had more treatments per week than the trials showing no difference in effect. In short one could say that LLLT should be used much in the same way as NSAID are used for short periods of time. Most trials showing significant effects used an IR 904 nm laser, but some results in favour of IR lasers with wavelengths of 780, 820 and 830 nm were also observed. Clinical effects of LLLT were best in subacute conditions. In chronic conditions a higher dosage and more treatments seem to be needed. The results of the high quality LLLT trials were all in favour of treatment with confidence intervals not including zero, and the trials came from several different research groups. Evidence was found to be at the highest or the second highest level depending on what level of clinical significance is decided according to the classicication of Oxman (1994) and McQuay (1997). The review found little support for the alleged large placebo effects of LLLT. In chronic cases the placebo effect is probably less that 10%, after the natural history of the complaints is taken into account.”
In the “Summary of discussion on clinical effect estimates for LLLT” the author writes:
“The majority of the included LLLT-trials found significant clinical effect from LLLT. Seven of the eleven LLLT-trials with acceptable methods included calculations of 95% confidence limits above zero, and one LLLT-trial on anke sprain included zero (Axelsen & Bjerno 1993). The clincal effect estimates from LLLT-trials for shoulder tendinitis/bursitis are similar or higher than for NSAID or steroid injections. For lateral epicondylalgia estimates for short term clinical effects are similar or lower for LLLT than for steroid injections, but medium clinical effect estimates are similar or higher for LLLT. Recurrence of symptoms in lateral epicondylalgia is less likely after LLLT than after steroid injections. Evidence of clinical effects from ankle sprain is inconclusive. Adverse effects from LLLT are seldom seen and they appear less serious than for patients treated with NSAID and steroid injections.”
Here are some selected mini-abstracts from the 2nd Congress World Association for Laser Therapy, September 2-5, 1998. Kansas City, MO, USA.
Parizotto tenectomized the achilles tendons in 32 rats and resutured the skin.
After 24 hours HeNe laser was applied, daily for ten days. Doses of 0.5, 5 and 50 J/cm2 were used. HeNe laser enhanced the intra- and intermolecular hydrogen bonding in the collagen molecules. The treated tendons were more organized than controls. Parizotto N A, Baranauskas V. Structural analysis of collagen fibrils after He-Ne laser photostimulated regenerating rat tendon. Proc. 2nd Congress World Assn for Laser Therapy, Kansas City, September 1998; p. 66
Onac compared the effect of HeNe
laser and monochromatic light at 618 nm.
Asagai reports on the use of
GaAlAs (100 mW) laser treatment in a group of 1000 patients with
Katsuyama studied the effect
of 830 nm laser in a neuropathic pain model of rat.
Phantom pain after amputations
is a severe problem.
In a study by Amaral 15 mice
received a single muscular injection of myotoxin
In an animal study by Kobayashi the
effect of GaAlAs laser on the blood flow in flaps was studied
through laser speckle flowgraphy (LSF).
Schindl treated a chronic radiation
ulcer with HeNe laser, 30 J/cm2.
55 patients with long lasting
chronic venous ulcers, suffering for more than 6 months without
improvement, were treated with LLLT by Lichtenstein .
In a study extended over 6 years Soriano
treated 231 patients with venous leg ulcers.
The effect of different
approaches for laser therapy of acute nonspecific epididymitis
was studied by Gomberg .
|Abstracts from 2001||Abstracts from 2000 June||Abstracts
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